Molecular Environmental BiologyMolecular Environmental Biology is the first book to illustrate molecular biological approaches to major issues in environmental biology. International experts have contributed representative chapters that cover how molecular methods and concepts apply to wildlife management, ecology, pollution control and remediation, and environmental health. Specific topics discussed include the use of molecular techniques in the population biology of wild animals and in the management of fisheries, bioremediation, cloning and characterization of the genes responsible for degradation of PCBs and related environmental pollutants, molecular analysis of aromatic hydrocarbon degradation by soil bacteria, and molecular biological techniques in assessing environmental damage to natural habitats. The book also explores how new molecular approaches can be applied to human disease etiology and epidemiology. Topics discussed in this area include an introduction to molecular epidemiology, the uses of molecular biological markers in cancer risk assessment, specific environmental carcinogens found in foods, measuring DNA adducts and mutation frequencies to assess environmental toxic exposures and effect, and using the extent of gene inducibility as a dosimeter of toxic exposure. This book will interest researchers and students in all fields of environmental biology and environmental medicine. Readers will find information on new techniques and applications of established molecular methodology that will stimulate new research ideas, collaborations, and progress. Researchers will now have a chance to make rapid progress on environmental questions that were previously not even open for exploration. |
ما يقوله الناس - كتابة مراجعة
لم نعثر على أي مراجعات في الأماكن المعتادة.
المحتوى
| 1 | |
| 11 | |
| 17 | |
| 29 | |
| 65 | |
| 73 | |
| 80 | |
Biodegradative Applications of the Cloned Genes | 104 |
Medical Genetics | 135 |
Cardiovascular Diseases | 141 |
Molecular Epidemiologic Approaches | 153 |
Molecular Dosimetry of Ingested Carcinogens | 177 |
Carcinogens in Cooked Meats and Colon Cancer | 188 |
Metabolic Parameters | 195 |
Molecular Analysis of Mutation Induced In Vivo | 207 |
A Marker of Exposure | 225 |
Assessment of Environmental Degradation | 117 |
Conclusions and Recommendations | 129 |
Conclusions | 240 |
عبارات ومصطلحات مألوفة
acid activity addition adducts aflatoxin agents analysis application approach assay associated Atlantic base biological blood cancer Cancer Res Carcinogenesis carcinogens catabolic cells chemical cloned compared compounds containing CYP1A mRNA degradation demonstrated detected determined dioxygenase disease diversity DNA adducts effects encoding Environ environmental enzymes example exposure expression factors Figure fish fragments frequency gene genetic genome genotypes glycophorin Hudson human hybridization identification increased indicated individuals induced initial involved isolated levels liver lung major markers measured metabolism metabolites methods Mitochondrial DNA molecular monitoring mtDNA mutations Nature observed oxidation pathway patients plasmid polymorphism populations present probes protein Pseudomonas putida recent region response restriction risk River samples sequences showed shown similar single smoking species stocks strain striped bass structure studies suggested techniques tissue toluene tomcod transcription urine variability variation vivo workers
مقاطع مشهورة
الصفحة 24 - Saiki, RK, Gelfand, DH, Stoffel, S., Scharf, SJ, Higuchi, R., Horn, GT, Mullis, KB, and Erlich, HA 1988. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.
الصفحة 151 - Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity.
الصفحة 244 - Watanabe, J. Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P450IA1 gene. FEBS Lett., 26i: 131-133, 1990.
الصفحة 149 - O'Neill IK (eds): Methods for Detecting DNA Damaging Agents in Humans: Applications in Cancer Epidemiology and Prevention, IARC Scientific Publications No.
الصفحة 131 - Porter EL. 1987. Review and perspective on the use of mixed-function oxygenase enzymes in biological monitoring.
الصفحة 174 - Bressac. B.. Kew. M.. Wands. J.. and Ozturk. M. Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa.
الصفحة 245 - Cousins RJ. 1985. Absorption, transport, and hepatic metabolism of copper and zinc: Special reference to metallothionein and ceruloplasmin.
