Introduction to Drug MetabolismNelson Thornes Publishers, 2001 - 256 من الصفحات Looks at both biochemical and physiological angles. Examples maintain clinical relevance so practical importance of subject can be appreciated. |
المحتوى
PATHWAYS OF DRUG METABOLISM | 1 |
ENZYMOLOGY AND MOLECULAR MECHANISMS OF DRUG | 37 |
Further reading | 84 |
حقوق النشر | |
10 من الأقسام الأخرى غير ظاهرة
طبعات أخرى - عرض جميع المقتطفات
عبارات ومصطلحات مألوفة
ability acid action activity addition animals antipyrine appears assessment binding blood body capacity cause cell changes Chapter chemicals clear clearance clinical compartment complex components compounds concentration conjugation considered cytochrome b5 cytochrome P450 decrease deficiency dependent diet discussed disease distribution dose drug metabolism drug-metabolising effects endogenous enzyme activity enzymes epoxide ethanol example excretion expression factors Figure formation function further gene genetic given giving glucuronic acid glucuronidation glutathione haem half-life hepatic hormones human hydrocarbons hydroxylation important increase indicated inducers influence inhibition interaction involved kidney known lead levels liver major measure mechanisms metabolised methods microsomal molecular normal noted oxidase oxidation paracetamol particular pathways Pharmacol pharmacological phase phenobarbitone plasma protein reactions receptor reduced reductase response resulting role seen shown similar specific steroid structure studies substantial substrate Table tissue toxicity various vitamin whereas xenobiotics